Code Aorta is a single-center, retrospective, prospective analysis, and quality improvement study. The study analyzes the data of patients admitted to Brigham and Women’s Hospital with acute aortic syndrome (AAS). The study is set to enroll 1,000 patients either admitted to inpatient service with an AAS or outpatients identified as having a history of an AAS. The primary objective of the study is to determine if improvements in coordination of care and systematic follow up in patients with AAS improve outcomes. The secondary objectives of this study are to determine the natural history of subtypes of AAS and to characterize risk markers that may be useful for prognosis or informing therapeutic decision-making including imaging characteristics, available blood tests, and clinical characteristics.

The Discharge eAlert study is a randomized controlled trial which investigates the impact of a computerized decision support strategy on patients at high risk of venous thromboembolisms (VTE). Discharge eAlert aims to increase the frequency of VTE prophylaxis in high-risk patients. The study aims to determine whether alerting physicians about the importance of VTE prophylaxis prior to the time of planned hospital discharge will lower the incidence of outpatient VTE. The two strategies implemented were devising a risk score that reliably and quickly identified patients of high-risk of VTE and randomizing high-risk patients without prophylaxis into an intervention group or control group.